Doctoral fellowship in insulin signaling and nutrient sensing pathways in C. elegans

Descriptif du sujet
Description of the subject

We are seeking a highly motivated PhD candidate to join our research team for an exciting project aimed at uncovering the molecular mechanisms by which TORC1 and S6K regulate insulin signaling. The project will focus on using Caenorhabditis elegans as a model organism, employing advanced molecular biology techniques such as CRISPR/Cas9 gene editing, confocal microscopy, and proteomic analysis to investigate nutrient sensing and insulin secretion pathways.

The successful candidate will explore how TORC1 and S6K proteins regulate insulin-like protein secretion in response to nutrient changes. This work has implications for better understanding diabetes, a critical public health issue worldwide.

Required profile

The ideal candidate for this project should have:

  • A Master's or Engineering degree in Molecular Biology, Genetics, or a related field.
  • Proficiency in molecular biology, biochemistry, and proteomics techniques.
  • Strong analytical skills
  • Experience with gene editing (CRISPR/Cas9) and familiarity with C. elegans, including genetic manipulation, creation of mutant strains, and conducting phenotypic analyses, is a plus.
  • Proficiency in English
Application file

un CV, une lettre de candidature, le projet de thèse, diplômes et relevés de notes. Il doit être envoyé par mail à : 

https://ueuromed.org/en/innovation/cedoc/inscription-au-cedoc

Please send the application before November 4, 2024 to:

Cedoc.admission@ueuromed.org & i.moukadiri@ueuromed.org

Supervisors

Prof. Salim BOUNOU, Euromed University of Fes (UEMF)  
Prof. Simon TUCK, Umeå University (Sweden)  
Prof. Ismail MOUKADIRI, Euromed University of Fes (UEMF)